Manufacturing

Our plant is situated in Ioannina, Northern Greece and comprises 5 units.

Our plant is situated in Ioannina, Northern Greece and comprises 5 units.

The main manufacturing sites are those for sterile products, non-sterile products, packaging of sterile & non sterile products, packaging of cytostatics (isolated  area) and cephalosporins (isolated area)

Our plant’s manufacturing activities & operations are EU GMP-certified for human & veterinary medicinal products, medical devices, food supplements and cosmetics; we are also under final approval for MA License for homeopathic products.

The Production Department is staffed with highly experienced personnel and is involved in the production of a wide range of pharmaceutical formulations, such as solid and semisolid products, tablets & capsules with pellets, powders, suppositories, gels & creams and liquid forms such as vials, ampoules, eye drop solutions, suspensions, syrups and solutions for external use.

Our annual production exceeds 7 million packages, accumulating more than 80 million units and 70 different item numbers. Our indicative daily capacity for various products is:

Non Sterile Products

  • Tablets (2.500.000 tabs/day)
  • Capsules (150.000 caps/day)
  • Pellets (100 Kg/day)
  • Sachets 1 (100.000 sachets/day)
  • Sachets 2 (160.000 sachets/day)
  • Gels/Creams (30.000 tubes/day (10g), 6.000 tubes /day (100g))
  • Suppositories (70.000 sups/day)
  • Nasal Sprays (30.000 vials/day (10ml))
  • Oral sol./Syrups (35.000 vials/day (10ml), 15.000 bottles/day (100ml))

Sterile Products

  • Ampoules line 1 (100.000 amps/day (2ml), 70.000 amps/day (5ml))
  • Ampoules line 2 (30.000 amps/day (3ml))
  • Vials (20.000 vials/day (2-5ml), 2.000 vials/day (100ml))
  • Eye drops (20.000 flacons/day (2-5ml))

Cephalosporins 

  •  Tablets (500.000 tabs/day)

The Quality Control (QC) Department, is in fully integration with our manufacturing process  and collaborates closely with the Production & QA Departments. The QC Department is divided into the Chemical & Microbiological sections, performing all the required analyses for acceptance of incoming goods, release of finished products, validations,  support for process & environmental validations and in-process control.

The Quality Assurance (QA) Department secures that the in-house processes and the products and services provided by help pharmaceuticals meet the internally set indicators and the customers’ specifications.

The QA Department is involved in: 

  • verification of cGMP compliance
  • documentation
  • SOP management
  • validation protocols
  • IQ/OQ/PQ of areas [machinery, equipment, ancillary systems]
  • product defects management [Deviations, Complaints, Recalls]
  • APQR performance
  • self-inspection system
  • personnel training

ESPA ESPA